Have you ever tried to learn about assisted fertility methods? If so, you will probably know that drug treatment is the first step of treatment that your doctor recommends. Among them, Clomiphene is the most commonly used drug.
Clomiphene is the brand name and its trade names are Clomid® and Serophene®. You can easily find out about the manufacturers of this drug through a number of reputable websites. To learn more about this fertility medicine, please find out through the following article!
This is fertility drugs in the case of:
You are ovulating irregularly or not, especially if you have polycystic ovary syndrome (PCOS);
You are infertile for no apparent reason;
You need to stimulate egg production before intrauterine insemination (IUI) or assisted reproductive technology (ART) treatment, such as in vitro fertilization (IVF).
Depending on your overall health, your doctor may prescribe drugs other than Clomiphene. In addition, you should also learn more about other fertility drugs.
This drug can cause a hormone imbalance in men. This results in poor sperm count and quality.
Some women have emotional impact on treatment because they are concerned about the body's response to the medication. It is best that they see their doctor regularly for follow-up.
Here, we will show you how Clomiphene works:
User manual. You should take one Clomiphene pill during the first 5 days of your menstrual cycle. In this way, the body produces many follicle-stimulating hormone (FSH) to grow. Ovarian cysts are sacs filled with fluid and also where eggs mature;
Signs of ovulation. After 5 days of taking Clomiphene, your brain releases a dose of luteinizing hormone (LH), which signals the ovaries to release one or more mature eggs. The LH surge occurs 5 to 12 days after your last dose of Clomiphene;
Time of ovulation. At this point, your doctor will follow closely to see if your ovaries are ready for ovulation. Through a blood test or ultrasound , the doctor will know how the follicle is developing. You can also use an ovulation predictor kit or body temperature chart to detect when you are ovulating;
Time of conception. By monitoring your ovulation, your doctor will determine the ideal time for you and your husband to have sex or the best time to pump sperm into the uterus. When an egg meets healthy sperm, your chances of conceiving are increased.
The duration of treatment depends on the menstrual cycle and the location of the woman, usually from 1–2 months. Before ovulation, your doctor may increase the dosage if needed. When ovulation, you may lose 3 to 6 treatments. Most doctors do not recommend taking Clomiphene any more if you have had more than 6 treatments.
When your menstrual cycle is regular: Clomiphene should be taken for 2 to 5 days during this period. To determine when to have your period, you should use an ovulation prediction kit;
When your period is irregular or absent: your doctor will prescribe medroxyprogesterone acetate for about 10 days to start your period. After your period, you will use Clomiphene.
If you are unsuccessful after 3 treatments, your doctor prescribes another medication or suggests you switch to another treatment.
Most women do respond well to Clomiphene, but others experience minor side effects, such as:
Mood swings;
Hot flashes;
Cervical mucus is thick and dry;
Pelvic pain;
Breast tenderness;
Endometrial cancer;
Nausea;
Headache;
Mild depression;
Blurred vision or double vision (this is less common).
The chance of having twins when you take Clomiphene is 5–12% and multiple pregnancies are less than 1%. Although many couples view multiple pregnancies as good news, it actually increases the risk of miscarriage, preterm birth, and other complications.
In rare cases, Clomiphene causes mild ovarian hyperstimulation syndrome (OHSS), leading to weight gain and a feeling of fullness. This happens when the ovaries respond well to fertility drugs and produce too many eggs. The ovaries rapidly hatch many times their normal size and release fluid that leaks into the abdomen.
Mild ovarian hyperstimulation will usually go away on its own with adequate rest and monitoring. In very rare cases, this syndrome can be life-threatening. At this point, you need hospital monitoring or more intensive supervision.
Recent studies have found that taking adjuvant drugs like Clomiphene does not increase the risk of developing ovarian cancer. In the past, this issue was a highly controversial question and received worldwide attention.
About 80% of women will ovulate in the first 3 months of treatment. Among them, 30 to 40% of women will get pregnant in the third treatment. However, the chance of having a baby depends on many factors, including age , sperm count and quality.
This article has provided useful information on the treatment of infertility with Clomiphene. Wish your family quickly have good news!
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